Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952759 | 0.79 | MAPT (0.52) | THRBMEN1KMT2AHTTMAPT | |
| SCHEMBL10430838 | 0.75 | RXRA (0.57) | RXRAHDAC3HDAC6ALDH1A1HPGD | |
| SCHEMBL11422095 | 0.75 | ALDH1A1 (0.50) | CYP1A2CYP3A4MEN1KMT2AHTT | |
| SCHEMBL8628395 | 0.74 | THRB (0.44) | THRBCYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL18872141 | 0.72 | RXRA (0.33) | THRBCYP1A2CYP3A4RXRA | |
| SCHEMBL6253133 | 0.71 | MAPT (0.43) | THRBCYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL646261 | 0.70 | ALDH1A1 (0.44) | CYP1A2CYP3A4MEN1KMT2ANPSR1 | |
| SCHEMBL4740356 | 0.69 | THRB (0.64) | THRBCYP1A2CYP3A4HTTNPSR1 | |
| SCHEMBL29612835 | 0.69 | THRB (0.52) | THRBCYP1A2CYP3A4HTTNPSR1 | |
| SCHEMBL30570427 | 0.68 | MAPT (0.56) | CYP1A2CYP3A4MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056623-A1 | DENTAL COMPOSITIONS CONTAINING LIQUIDS AND OTHER ELASTOMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |