SCHEMBL10434286

SCHEMBL10434286

Cc1ccc(C(=CC(C=C(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
TDP1 Q9NUW8 4/20 0.40
HTT P42858 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
PKM P14618 2/20 0.40
ATM Q13315 2/20 0.40
HPGD P15428 2/20 0.40
NLRP1 Q9C000 1/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 1/20 0.40
NTSR1 P30989 1/20 0.40
KMT2A Q03164 1/20 0.40
CES2 O00748 2/20 0.39
CES1 P23141 2/20 0.39
ACHE P22303 2/20 0.39
PTGS2 P35354 1/20 0.37
CHRNA7 P36544 1/20 0.37
MAPT P10636 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615901 0.78 ALDH1A1 (0.45) ALDH1A1TDP1HPGDGAAMEN1
SCHEMBL10433799 0.74 LMNA (0.48) ALDH1A1TDP1HTTNPSR1LMNA
SCHEMBL10613825 0.73 L3MBTL1 (0.41) ALDH1A1TDP1NPSR1LMNACES2
SCHEMBL10433950 0.72 CES2 (0.42) ALDH1A1NPSR1LMNASMN1; SMN2HPGD
SCHEMBL6763915 0.71 ALDH1A1 (0.50) ALDH1A1TDP1HTTNPSR1LMNA
SCHEMBL1244260 0.68 ALOX5 (0.43) ALDH1A1TDP1HTTNPSR1LMNA
SCHEMBL158242 0.67 CHRNA7 (0.42) ALDH1A1TDP1SMN1; SMN2GAAMEN1
SCHEMBL548390 0.67 CYP2A6 (0.46) ALDH1A1TDP1HTTNPSR1LMNA
SCHEMBL516740 0.67 ALDH1A1 (0.46) ALDH1A1TDP1HTTNPSR1LMNA
SCHEMBL14189755 0.67 PDE4A (0.55) ALDH1A1TDP1HTTNPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0388768-A2 Organic electroluminescent device containing aromatic dimethylidyne compounds IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-09-26 EP disclosed