SCHEMBL10433799

SCHEMBL10433799

Cc1ccc(C(C=C(c2ccccc2)c2ccccn2)C=C(c2ccccc2)c2ccccn2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.48
KMT2A Q03164 4/20 0.48
MEN1 O00255 2/20 0.48
OPRK1 P41145 2/20 0.48
ALDH1A1 P00352 2/20 0.48
CHRM1 P11229 1/20 0.48
ADRA2B P18089 1/20 0.48
SLC6A4 P31645 1/20 0.48
ADRA1A P35348 1/20 0.48
HRH1 P35367 1/20 0.48
KCNH2 Q12809 1/20 0.48
CYP2D6 P10635 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
THPO P40225 1/20 0.48
GMNN O75496 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NPC1 O15118 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22660166 0.74 KMT2A (0.55) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL10434286 0.74 ALDH1A1 (0.40) LMNAKMT2AMEN1ALDH1A1NPSR1
SCHEMBL8999123 0.74 KMT2A (0.53) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL8999119 0.74 KMT2A (0.53) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL10433950 0.72 CES2 (0.42) LMNAKMT2AMEN1ALDH1A1TSHR
SCHEMBL10613825 0.70 L3MBTL1 (0.41) LMNAALDH1A1CYP2D6TSHRNPSR1
SCHEMBL24704170 0.69 RAB9A (0.49) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL10620307 0.69 RAB9A (0.49) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL10620312 0.69 RAB9A (0.49) LMNAKMT2AMEN1OPRK1ALDH1A1
SCHEMBL2773353 0.68 CYP19A1 (0.56) LMNAKMT2AALDH1A1CYP2D6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0388768-A2 Organic electroluminescent device containing aromatic dimethylidyne compounds IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-09-26 EP disclosed