Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | STAT5B | P51692 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673134 | 0.70 | MGLL (0.52) | MGLLALDH1A1HPGDHSD11B1POLB | |
| SCHEMBL10437623 | 0.70 | MEN1 (0.46) | MGLLALDH1A1HPGDHSD11B1STAT5B | |
| SCHEMBL9769828 | 0.70 | ELANE (0.43) | MGLLALDH1A1HPGDMAPTHSD11B1 | |
| SCHEMBL9769831 | 0.68 | ALDH1A1 (0.42) | MGLLALDH1A1HPGDHSD11B1STAT5B | |
| SCHEMBL10611755 | 0.67 | HMGCR (0.37) | MGLLALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL9769894 | 0.66 | ALDH1A1 (0.43) | MGLLALDH1A1HPGDHSD11B1STAT5B | |
| SCHEMBL12781922 | 0.66 | MGLL (0.51) | MGLLALDH1A1HPGDMAPTHSD11B1 | |
| SCHEMBL9769841 | 0.64 | HMGCR (0.41) | MGLLALDH1A1HPGDMAPTHSD11B1 | |
| SCHEMBL9769846 | 0.64 | HMGCR (0.41) | MGLLALDH1A1HPGDMAPTHSD11B1 | |
| SCHEMBL10609361 | 0.64 | TDP1 (0.37) | MGLLALDH1A1MAPTELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355820-A1 | Antihypercholesterolemic tetrazol-1-yl compounds | Bristol-Myers Squibb Company (US) | 1990-02-28 | — | — | EP | disclosed |