Leucine

SCHEMBL10439243

CC(C)C[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@@H](OC(=O)[C@@H](N)[C@@H](C)OC(=O)[C@@H](N)CO)[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)OC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1c[nH]cn1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	APLNR	P35414	2/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Arginine SCHEMBL8510534	0.82	CTSL (0.31)	APLNR
Arginine SCHEMBL285822	0.79	FNTA (0.35)	APLNR
Arginine SCHEMBL27607779	0.78	APLNR (0.36)	APLNR
Lysine SCHEMBL16762311	0.78	NPY4R (0.32)	—
Arginine SCHEMBL23362144	0.77	FNTA (0.37)	APLNR
Arginine SCHEMBL8512347	0.77	FNTA (0.37)	APLNR
Arginine SCHEMBL181305	0.77	APLNR (0.31)	APLNR
Arginine SCHEMBL181614	0.77	APLNR (0.31)	APLNR
Tyrosine SCHEMBL27557772	0.76	NPY4R (0.46)	APLNR
Arginine SCHEMBL9751283	0.76	APLNR (0.33)	APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0366239-A1	Purification process for recombinant influenza proteins	SMITHKLINE BEECHAM CORPORATION (US)	1990-05-02	—	—	EP	disclosed
EP-0366238-A2	Influenza vaccinal polypeptides	SMITHKLINE BEECHAM CORPORATION (US)	1990-05-02	—	—	EP	disclosed