Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9458661 | 0.99 | CYP2D6 (0.39) | CYP2D6CNR1CNR2HRH3HSD11B1 | |
| SCHEMBL6475630 | 0.75 | ALOX5 (0.45) | PTGS1ALOX5MEN1KMT2A | |
| SCHEMBL9537195 | 0.73 | PTGS2 (0.49) | HRH3HSD11B1PTGS1ALOX5PTGS2 | |
| SCHEMBL9458748 | 0.68 | ALOX5 (0.46) | PTGS1ALOX5 | |
| SCHEMBL9458649 | 0.68 | PTGES (0.44) | PTGS1ALOX5PTGS2 | |
| SCHEMBL9472243 | 0.68 | PTGS2 (0.49) | HRH3PTGS1ALOX5PTGS2 | |
| SCHEMBL11211021 | 0.65 | HRH3 (0.58) | CYP2D6CNR2HRH3HSD11B1 | |
| SCHEMBL5672731 | 0.62 | SOAT1 (0.54) | — | |
| SCHEMBL1026184 | 0.62 | PPARA (0.53) | HSD11B1 | |
| SCHEMBL5555116 | 0.62 | GCGR (0.50) | CNR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397175-A1 | Substituted pyrrolizine compounds and theit use as pharmaceuticals | Dannhardt, Gerd, Prof.Dr. (DE) | 1990-11-14 | — | — | EP | disclosed |