Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15199343 | 0.88 | ACHE (0.53) | CA2CA12CA9CA1CA3 | |
| SCHEMBL6903823 | 0.82 | NR3C2 (0.53) | CA2CA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL17341893 | 0.80 | CA2 (0.50) | CA2CA12CA9CA1CA3 | |
| SCHEMBL3046201 | 0.79 | CA2 (0.65) | CA2CA12CA9CA1CA3 | |
| SCHEMBL9765329 | 0.78 | MEN1 (0.51) | CA2CA1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10448561 | 0.78 | KEAP1 (0.53) | CA2CA12CA9CA1ALDH1A1 | |
| SCHEMBL14061940 | 0.77 | CA2 (0.69) | CA2CA12CA9CA1CA3 | |
| SCHEMBL18726029 | 0.76 | CA12 (0.54) | CA2CA12CA9CA1ALDH1A1 | |
| SCHEMBL14676346 | 0.76 | CA2 (0.56) | CA2CA12CA9CA1CA3 | |
| SCHEMBL21690373 | 0.75 | DUT (0.56) | ALDH1A1MAPTSMN1; SMN2GAADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375557-A1 | Glycine derivative process for preparation thereof, and pharmaceutical composition containing it | TANABE SEIYAKU CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |