Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DUT | P33316 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903823 | 0.88 | NR3C2 (0.53) | KEAP1KMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL9765329 | 0.83 | MEN1 (0.51) | KMT2AMEN1CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL21690373 | 0.83 | DUT (0.56) | KEAP1CYP2C19ALDH1A1MAPTDUT | |
| SCHEMBL1409455 | 0.80 | DUT (0.56) | KEAP1CYP2C19ALDH1A1MAPTDUT | |
| SCHEMBL10448367 | 0.78 | CA2 (0.55) | KMT2AMEN1ALDH1A1MAPTDUT | |
| SCHEMBL18726029 | 0.78 | CA12 (0.54) | KEAP1KMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL27827531 | 0.77 | DUT (0.54) | KMT2AMEN1CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL15199346 | 0.75 | ALDH1A1 (0.57) | KMT2AMEN1CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL2408403 | 0.74 | ALDH1A1 (0.59) | KMT2AMEN1CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL21360262 | 0.74 | FFAR4 (0.49) | KMT2AMEN1CYP2C19ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375557-A1 | Glycine derivative process for preparation thereof, and pharmaceutical composition containing it | TANABE SEIYAKU CO., LTD. (JP) | 1990-06-27 | — | — | EP | disclosed |