Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.35 |
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542953 | 0.90 | PGR (0.42) | CYP19A1PGR | |
| SCHEMBL10449145 | 0.85 | CYP19A1 (0.39) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL10697075 | 0.83 | CYP19A1 (0.38) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL8538436 | 0.80 | CYP19A1 (0.35) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL8536672 | 0.78 | PDK1 (0.38) | SHBGALDH1A1PGR | |
| SCHEMBL9948623 | 0.75 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL6301569 | 0.74 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL4945163 | 0.74 | SHBG (0.48) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL3356889 | 0.74 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 | |
| SCHEMBL9947828 | 0.73 | CYP19A1 (0.42) | CYP19A1SHBGSERPINA6SLC22A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843933-A | 11β-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| US-5728689-A | ANTIGESTAGENIC EFFECT | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |