Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417815 | 0.83 | CA2 (0.38) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL2133713 | 0.83 | CTSK (0.39) | CA2CA1CTSKCTSS | |
| SCHEMBL10451644 | 0.82 | ALDH1A1 (0.42) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL10451509 | 0.80 | CA2 (0.50) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL20361871 | 0.80 | CA2 (0.50) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL4907463 | 0.80 | CA2 (0.50) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL10695428 | 0.79 | CA2 (0.50) | CA2CA1CTSKMAPK1CYP3A4 | |
| SCHEMBL11977585 | 0.78 | ZDHHC7 (0.36) | CA2CA1CTSKCTSS | |
| SCHEMBL10451486 | 0.78 | L3MBTL1 (0.37) | CA2CA1MAPK1CYP3A4TSHR | |
| SCHEMBL14079863 | 0.78 | ZDHHC7 (0.36) | CA2CA1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4839381-A | FUNGICIDES, PESTICIDES; RICE PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-13 | — | — | US | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| US-4757085-A | Pharmaceuticals | BAYER AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |