Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330207 | 0.91 | NPC1 (0.40) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL401165 | 0.77 | CES2 (0.46) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL11313782 | 0.76 | CES2 (0.41) | CES2CES1CA1CA2SMN1; SMN2 | |
| SCHEMBL11319329 | 0.76 | HTR7 (0.39) | CES2CES1CA1CA2HPGD | |
| SCHEMBL29712522 | 0.75 | CES2 (0.44) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL2873871 | 0.75 | ALDH1A1 (0.44) | CES2CES1CYP3A4HPGDSMN1; SMN2 | |
| SCHEMBL29712521 | 0.75 | CES2 (0.44) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL647841 | 0.74 | TDP1 (0.40) | CES2CES1CA1CA2CYP3A4 | |
| SCHEMBL11322005 | 0.73 | HTR7 (0.44) | CES2CES1HPGDNPC1RAB9A | |
| SCHEMBL11326810 | 0.72 | MAOA (0.33) | CES2CES1CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256518-B1 | THERMOPLASTIC POLYMER COMPOSITIONS | MILLIKEN & CO (US) | 2021-05-05 | — | — | EP | disclosed |
| US-10745538-B2 | Thermoplastic polymer compositions | MILLIKEN & COMPANY (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190233614-A1 | THERMOPLASTIC POLYMER COMPOSITIONS | MILLIKEN & COMPANY | 2019-08-01 | — | — | US | disclosed |
| US-10273346-B2 | Thermoplastic polymer compositions | MILLIKEN & COMPANY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20160229986-A1 | THERMOPLASTIC POLYMER COMPOSITIONS | MILLIKEN & COMPANY | 2016-08-11 | — | — | US | disclosed |
| US-20160229986-A1 | THERMOPLASTIC POLYMER COMPOSITIONS | MILLIKEN & COMPANY | 2016-08-11 | — | — | US | disclosed |