Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | POLQ | O75417 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4849605 | 0.81 | DAO (0.44) | DAOPLK1PLK3RXRARXRB | |
| SCHEMBL29702020 | 0.71 | ALDH1A1 (0.43) | DAOPLK1HDAC6ALDH1A1HPGD | |
| SCHEMBL6293963 | 0.70 | ALDH1A1 (0.46) | RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8047110 | 0.69 | ALDH1A1 (0.41) | DAORXRARXRBALDH1A1HPGD | |
| SCHEMBL424607 | 0.69 | POLQ (0.40) | POLQRXRARXRBRXRGALDH1A1 | |
| SCHEMBL28678120 | 0.69 | CYP2C8 (0.49) | HDAC1HDAC6RXRARXRBRXRG | |
| SCHEMBL504216 | 0.69 | CA12 (0.46) | DAOPLK1PLK3RXRARXRB | |
| SCHEMBL21312967 | 0.68 | GABRA1 (0.46) | POLQLMNASMN1; SMN2 | |
| SCHEMBL7565059 | 0.68 | DAO (0.42) | DAOPLK1PLK3RXRARXRB | |
| SCHEMBL19585735 | 0.68 | DAO (0.42) | DAORXRARXRBRXRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187462-B1 | SUPPORTED OLEFIN POLYMERIZATION CATALYST | AMOCO CORPORATION (US) | 1990-04-25 | — | — | EP | claimed |