Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679919 | 0.99 | MAPT (0.48) | MAPTGFERSMN1; SMN2TP53MEN1 | |
| SCHEMBL10458636 | 0.83 | THRB (0.44) | MAPTSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL9681734 | 0.83 | CYP3A4 (0.54) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9680457 | 0.82 | GSK3B (0.49) | MAPTSMN1; SMN2TP53GAALMNA | |
| SCHEMBL12013268 | 0.82 | LMNA (0.43) | MAPTSMN1; SMN2LMNATHRBHPGD | |
| SCHEMBL10458802 | 0.82 | ATM (0.43) | MAPTSMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL274970 | 0.82 | SMN1; SMN2 (0.51) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10456871 | 0.81 | CYP3A4 (0.55) | MAPTSMN1; SMN2KMT2ALMNAHPGD | |
| SCHEMBL12855171 | 0.80 | THRB (0.44) | SMN1; SMN2KMT2ALMNATHRBHPGD | |
| SCHEMBL306036 | 0.79 | THRB (0.44) | SMN1; SMN2KMT2ALMNATHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0138754-B1 | PHOTOCURABLE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1988-05-25 | — | — | EP | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |