Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942698 | 0.85 | L3MBTL1 (0.56) | L3MBTL1POLBTDP1MEN1GAA | |
| SCHEMBL7477856 | 0.79 | PARP1 (0.57) | PARP1 | |
| SCHEMBL10723745 | 0.77 | XDH (0.47) | L3MBTL1POLBTDP1MEN1GAA | |
| SCHEMBL10466702 | 0.77 | CHEK1 (0.45) | L3MBTL1POLBTDP1MEN1GAA | |
| SCHEMBL10467865 | 0.76 | PKN1 (0.53) | TDP1MEN1GAAMAPTKMT2A | |
| SCHEMBL3287778 | 0.74 | MEN1 (0.58) | L3MBTL1POLBTDP1MEN1GAA | |
| SCHEMBL30291834 | 0.74 | MEN1 (0.58) | L3MBTL1POLBTDP1MEN1GAA | |
| SCHEMBL830431 | 0.73 | L3MBTL1 (0.68) | L3MBTL1POLBMEN1GAAMAPT | |
| SCHEMBL29815201 | 0.73 | L3MBTL1 (0.68) | L3MBTL1POLBMEN1GAAMAPT | |
| SCHEMBL516619 | 0.72 | NUDT1 (0.56) | MAPTKMT2ACA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | claimed |
| US-4943570-A | GASTROINTESTINAL DISORDERS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-07-24 | — | — | US | disclosed |
| US-4933338-A | ANTIULCER AGENTS, ANTISECRETORY AGENTS, TREATMENT OF GASTROINTESTINAL DISORDERS; CHEMICAL INTERMEDIATES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1990-06-12 | — | — | US | disclosed |
| EP-0246126-A1 | Benzimidazoles and imidazopyridine sulfone amides, process for their preparation and their use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1987-11-19 | — | — | EP | disclosed |