Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCKDK | O14874 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10469338 | 0.92 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL4870613 | 0.80 | NOS3 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL10341772 | 0.68 | KMT2A (0.40) | NOS3NOS1 | |
| SCHEMBL10341774 | 0.68 | KMT2A (0.40) | NOS3NOS1 | |
| SCHEMBL4865586 | 0.63 | MAOA (0.34) | — | |
| SCHEMBL30800875 | 0.62 | GPR3 (0.61) | BCKDKSENP1 | |
| SCHEMBL4866851 | 0.62 | GPR3 (0.61) | BCKDKSENP1 | |
| SCHEMBL10468020 | 0.60 | NOS3 (0.39) | NOS3NOS1NOS2 | |
| SCHEMBL10469339 | 0.60 | MAPT (0.62) | BCKDK | |
| SCHEMBL4514959 | 0.60 | ALDH1A1 (0.52) | BCKDK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342433-A2 | Substituted dibenzothiaphenes | AMERICAN CYANAMID COMPANY (US) | 1989-11-23 | — | — | EP | disclosed |