Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426506 | 0.91 | TSHR (0.42) | TSHRTHRBALDH1A1BTN3A1POLB | |
| SCHEMBL3447863 | 0.83 | TSHR (0.50) | TSHRTHRBPLA2G2A | |
| SCHEMBL28221578 | 0.79 | TSHR (0.35) | TSHRPLA2G2A | |
| SCHEMBL31091982 | 0.77 | THRB (0.55) | TSHRTHRBALDH1A1BTN3A1POLB | |
| SCHEMBL15194 | 0.77 | THRB (0.55) | TSHRTHRBALDH1A1BTN3A1POLB | |
| Ammonia Solution, Strong SCHEMBL18140715 | 0.75 | THRB (0.53) | TSHRTHRBALDH1A1BTN3A1POLB | |
| Phosphoric Acid SCHEMBL11307097 | 0.75 | THRB (0.53) | TSHRTHRBALDH1A1BTN3A1POLB | |
| SCHEMBL1447880 | 0.75 | THRB (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Bromoethane SCHEMBL3220997 | 0.74 | THRB (0.53) | TSHRTHRBALDH1A1BTN3A1POLB | |
| SCHEMBL27969779 | 0.74 | CYP3A4 (0.49) | TSHRTHRBALDH1A1TDP1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998417-B2 | Process for producing a surface-modified dental article | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-06-04 | — | — | US | disclosed |
| EP-4035649-B1 | DENTAL ADHESIVE COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-07-26 | — | — | EP | disclosed |
| US-20230225829-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2023-07-20 | — | — | US | disclosed |
| EP-4175584-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | 3M Innovative Properties Company (US) | 2023-05-10 | — | — | EP | disclosed |
| EP-3508190-B1 | LIGHT CURABLE COMPOSITION | TOKUYAMA DENTAL CORP (JP) | 2022-02-09 | — | — | EP | disclosed |
| EP-3706708-B1 | RADIOPAQUE DENTAL COMPOSITION | 3M INNOVATIVE PROPERTIES CO (US) | 2022-01-12 | — | — | EP | disclosed |
| WO-2022003470-A1 | PROCESS FOR PRODUCING A SURFACE-MODIFIED DENTAL ARTICLE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-01-06 | — | — | WO | disclosed |
| US-20210395419-A1 | STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2021-12-23 | — | — | US | disclosed |
| US-11160733-B2 | Dental adhesive composition, preparation and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| EP-3880156-A1 | STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION | 3M Innovative Properties Company (US) | 2021-09-22 | — | — | EP | disclosed |
| EP-2108663-A1 | POLYMERIZABLE MONOMER, POLYMERIZABLE COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| EP-2108664-A1 | COMPOSITION AND DENTAL MATERIAL | Kuraray Medical Inc. (JP) | 2009-10-14 | — | — | EP | disclosed |
| EP-1285947-B1 | ANTIMICROBIAL COMPOSITION | KURARAY CO (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-20070100020-A1 | One-pack type adhesive composition for dental use | KURARAY MEDICAL INC. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1695685-A1 | ONE-PACK TYPE ADHESIVE COMPOSITION FOR DENTAL USE | Kuraray Medical Inc. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6887920-B2 | Fillings and composite dental materials containing the fillings | KURARAY CO., LTD. (JP) | 2005-05-03 | — | — | US | disclosed |
| US-20030064102-A1 | Antimicrobial Composition | NAKATSUKA KAZUMITSU (JP) | 2003-04-03 | — | — | US | disclosed |
| US-20030060533-A1 | A metal oxide and a water-soluble metal salt each forming an independent phase; high water resistance and high acid resistance, and high releasing abilities of ions such as fluorine ions | KURARAY NORITAKE DENTAL INC. (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1285947-A1 | ANTIMICROBIAL COMPOSITION | KURARAY CO., LTD. (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-1270688-A1 | FILLINGS AND COMPOSITE DENTAL MATERIALS CONTAINING THE FILLINGS | KURARAY CO., LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100020-A1 | One-pack type adhesive composition for dental use | CDH1, COL1A1, COL2A1 | TSHR 4681/4885THRB 3925/4885ALDH1A1 419/4885 |
| US-20210395419-A1 | STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION | DUOX2, GPX4, PRDX2 | TSHR 4492/4885THRB 4432/4885ALDH1A1 376/4885 |
| US-20030064102-A1 | Antimicrobial Composition | AAAS, H1-0, H1-10 | TSHR 4699/4885THRB 3108/4885ALDH1A1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.