Sugi Predict

Sugi Predict / Compounds / SCHEMBL104732

SCHEMBL104732

SCHEMBL104732

CC(C)Oc1cccc(F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.51
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ SLC6A4 P31645 1/20 0.47
▸ PPARG P37231 1/20 0.47
▸ PPARA Q07869 1/20 0.47
▸ RXRA P19793 1/20 0.46
▸ RXRB P28702 1/20 0.46
▸ GAA P10253 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ NFE2L2 Q16236 1/20 0.43
▸ ACHE P22303 1/20 0.43
▸ NPC1 O15118 2/20 0.42
▸ RAB9A P51151 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ NFKB1 P19838 1/20 0.42
▸ NFKB2 Q00653 1/20 0.42
▸ RELA Q04206 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4957584 0.92 HPGD (0.50) HPGDMEN1KMT2AATMSLC6A4
Formic Acid SCHEMBL26108633 0.89 HPGD (0.55) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL2968363 0.84 RXRA (0.53) MEN1KMT2ARXRARXRBGAA
SCHEMBL23067916 0.83 HPGD (0.49) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL1619629 0.83 HPGD (0.49) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL3168184 0.83 HPGD (0.49) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL96595 0.80 HPGD (0.54) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL7154353 0.80 HPGD (0.50) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL14604949 0.80 HPGD (0.47) HPGDMEN1KMT2AATMSLC6A4
SCHEMBL16294967 0.80 PPARG (0.53) HPGDMEN1KMT2AATMSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124410-B Preparation method of 2-fluoro-4-hydroxybenzaldehyde 上海珂华生物科技有限公司 2024-06-04 — — CN claimed
CN-110157109-A A kind of moisture-proof high intensity IC carrier material 浙江三和塑料有限公司 2019-08-23 — — CN claimed
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2025-06-24 — — US disclosed
CN-115124410-B Preparation method of 2-fluoro-4-hydroxybenzaldehyde 上海珂华生物科技有限公司 2024-06-04 — — CN disclosed
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT VALO HEALTH, INC. 2023-11-02 — — US disclosed
US-20230148061-A1 TEAD INHIBITORS AND USES THEREOF THE EHE FOUNDATION 2023-05-11 — — US disclosed
US-20230148061-A1 TEAD INHIBITORS AND USES THEREOF THE EHE FOUNDATION 2023-05-11 — — US disclosed
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2023-01-10 — — US disclosed
US-11058676-B2 Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof PHARMAKEA, INC. (US) 2021-07-13 — — US disclosed
US-10428080-B2 TBK/IKK inhibitor compounds and uses thereof MERCK PATENT GMBH (DE) 2019-10-01 — — US disclosed
CN-110157109-A A kind of moisture-proof high intensity IC carrier material 浙江三和塑料有限公司 2019-08-23 — — CN disclosed
EP-0232776-B1 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1990-10-24 — — EP disclosed
EP-0389162-A1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1990-09-26 — — EP disclosed
EP-0365678-A1 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF TORAY INDUSTRIES, INC. (JP) 1990-05-02 — — EP disclosed
US-4801717-A PLANT GROWTH REGULATORS ROUSSEL UCLAF (FR) 1989-01-31 — — US disclosed
US-4775692-A ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT TORAY INDUSTRIES, INC. (JP) 1988-10-04 — — US disclosed
EP-0232776-A2 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1987-08-19 — — EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same — 1987-07-29 — — CN disclosed
EP-0119892-B1 HYDROXYL AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS GROWTH FACTORS FOR VEGETABLES AND COMPOSITIONS THEREOF ROUSSEL-UCLAF (FR) 1986-08-13 — — EP disclosed
EP-0119892-A1 Hydroxyl amine derivatives, their preparation, their use as growth factors for vegetables and compositions thereof ROUSSEL-UCLAF (FR) 1984-09-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230148061-A1 TEAD INHIBITORS AND USES THEREOF TEAD2, TEAD3, TEAD4 HPGD 223/4885MEN1 3307/4885KMT2A 2717/4885
US-10428080-B2 TBK/IKK inhibitor compounds and uses thereof NFKBIA, TBKBP1, TBK1 HPGD 2468/4885MEN1 4009/4885KMT2A 2730/4885
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NNT HPGD 188/4885MEN1 491/4885KMT2A 912/4885
US-11058676-B2 Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof LOXL2, LOXL1, LOX HPGD 241/4885MEN1 3988/4885KMT2A 796/4885
US-11547701-B2 Compounds and compositions for the inhibition of NAMPT NAMPT, NNMT, NQO1 HPGD 173/4885MEN1 473/4885KMT2A 908/4885
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT NAMPT, NNMT, NQO1 HPGD 321/4885MEN1 582/4885KMT2A 1615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.