SCHEMBL10475813

SCHEMBL10475813

C=C(C)C(=O)OC(C(=O)OCC)C(F)(F)F

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
TSHR P16473 4/20 0.39
ALDH1A1 P00352 6/20 0.34
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
GLO1 Q04760 1/20 0.32
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12186492 0.85 HTT (0.44) THRBTSHRALDH1A1
SCHEMBL26893069 0.81 HTT (0.34) THRBTSHR
SCHEMBL10475855 0.78 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL20924746 0.77 ALDH1A1 (0.32) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL7074875 0.76 THRB (0.47) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL28810373 0.75 THRB (0.47) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL1655798 0.74 TSHR (0.48) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL15721249 0.74 THRB (0.42) THRBTSHRALDH1A1LMNAHSD17B10
SCHEMBL20924749 0.74 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL8600304 0.74 ALDH1A1 (0.39) TSHRALDH1A1LMNAHSD17B10MGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479614-B1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORP (JP) 2019-07-24 EP disclosed
EP-2781959-B1 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORP (JP) 2019-04-24 EP disclosed
EP-2781959-B1 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORP (JP) 2019-04-24 EP disclosed
US-9513548-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2016-12-06 US disclosed
US-9513548-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2016-12-06 US disclosed
US-9513548-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2016-12-06 US disclosed
US-20160179003-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2016-06-23 US disclosed
US-20160179003-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2016-06-23 US disclosed
US-20160179003-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2016-06-23 US disclosed
EP-2781959-A2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR Corporation (JP) 2014-09-24 EP disclosed
US-20140212813-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2014-07-31 US disclosed
US-8728706-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8728706-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8728706-B2 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20120237875-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2012-09-20 US disclosed
US-20120237875-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2012-09-20 US disclosed
US-20120237875-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR CORPORATION (JP) 2012-09-20 US disclosed
EP-2479614-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR Corporation (JP) 2012-07-25 EP disclosed
EP-2479614-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR Corporation (JP) 2012-07-25 EP disclosed
WO-2011034176-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND JSR株式会社 (JP) 2011-03-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120237875-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN, POLYMER AND POLYMERIZABLE COMPOUND RER1, RDX, PRXL2A THRB 3768/4885TSHR 1194/4885ALDH1A1 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.