Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102736 | 0.88 | IDO1 (0.42) | IDO1ALDH1A1GAAKMT2ALMNA | |
| SCHEMBL13781132 | 0.81 | MGLL (0.48) | IDO1EPHX2ALDH1A1ALOX12HPGD | |
| SCHEMBL6264849 | 0.78 | IDO1 (0.59) | IDO1ALDH1A1KMT2ASMN1; SMN2HTT | |
| SCHEMBL5666794 | 0.74 | NOS1 (0.52) | IDO1ALDH1A1ALOX12HPGDGAA | |
| SCHEMBL13377788 | 0.74 | MGLL (0.41) | IDO1ALDH1A1ALOX12HPGDGAA | |
| SCHEMBL4804794 | 0.73 | CES2 (0.50) | IDO1ALDH1A1ALOX12HPGDGAA | |
| SCHEMBL23252514 | 0.73 | CES2 (0.44) | IDO1EPHX2CES2CES1AKR1B1 | |
| SCHEMBL8325341 | 0.73 | ALDH1A1 (0.45) | IDO1ALDH1A1ALOX12HPGDGAA | |
| SCHEMBL7324968 | 0.73 | ALDH1A1 (0.45) | IDO1ALDH1A1ALOX12HPGDGAA | |
| SCHEMBL7324963 | 0.73 | PAM (0.59) | EPHX2ALDH1A1HPGDGAACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048750-A1 | VESICULATED POLYMER PARTICLES | THE UNIVERSITY OF SYDNEY (AU) | 2010-02-25 | — | — | US | disclosed |
| WO-1989008830-A1 | THIOACYLATION PEPTIDE SEQUENCING WITH ALCOHOLYSIS OF THIAZOLINONES | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| US-4863870-A | Method of thioacylation peptide sequencing with alcoholysis of thiazolinones | BIO-AFFINITY SYSTEMS, INC. (US) | 1989-09-05 | — | — | US | disclosed |