Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792500 | 0.73 | MAPT (0.45) | ALDH1A1LMNAGAAPTPN1PTPN2 | |
| SCHEMBL10480341 | 0.72 | PTPN2 (0.48) | ALDH1A1LMNAGAAALOX15TDP1 | |
| SCHEMBL10480337 | 0.72 | PTPN2 (0.48) | ALDH1A1LMNAGAAALOX15TDP1 | |
| SCHEMBL2123396 | 0.72 | MAPT (0.50) | ALDH1A1LMNAGAAALOX15TDP1 | |
| SCHEMBL86097 | 0.71 | MAPT (0.48) | ALDH1A1LMNAGAA | |
| SCHEMBL2147325 | 0.71 | MAPT (0.48) | ALDH1A1LMNAGAAALOX15TDP1 | |
| SCHEMBL28291990 | 0.70 | CA1 (0.47) | ALDH1A1FAAH | |
| SCHEMBL7909119 | 0.70 | HDAC3 (0.49) | ALDH1A1LMNAGAAPTPN2FAAH | |
| SCHEMBL11763172 | 0.70 | LMNA (0.44) | ALDH1A1LMNAGAAALOX15TDP1 | |
| SCHEMBL28409963 | 0.69 | NPC1 (0.50) | ALDH1A1LMNAGAAALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822809-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1989-04-18 | — | — | US | disclosed |