Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 4/20 | 0.36 |
| ▸ | ANPEP | P15144 | 5/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318557 | 0.78 | FDPS (0.46) | FDPSLMNALAP3ANPEPGRM4 | |
| SCHEMBL10881877 | 0.71 | FDPS (0.37) | FDPSLMNALAP3ANPEPERAP2 | |
| SCHEMBL7962142 | 0.71 | LMNA (0.45) | FDPSLMNALAP3PGK1PGK2 | |
| SCHEMBL16143956 | 0.69 | LMNA (0.43) | FDPSLMNALAP3PGK1PGK2 | |
| SCHEMBL723967 | 0.69 | LMNA (0.38) | FDPSLMNAPGK1PGK2 | |
| SCHEMBL8087725 | 0.67 | FDPS (0.40) | FDPSLMNALAP3ANPEPERAP1 | |
| Phosphoric Acid SCHEMBL1831540 | 0.65 | — | — | |
| SCHEMBL5355267 | 0.65 | — | — | |
| SCHEMBL366377 | 0.65 | — | — | |
| SCHEMBL2982314 | 0.65 | LMNA (0.39) | FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070009981-A1 | Nematode phosphoethanolamine N-methyltransferase-like sequences | MONSANTO TECHNOLOGY LLC | 2007-01-11 | — | — | US | claimed |
| EP-1390759-B1 | ASSAY METHOD FOR PLATELET-ACTIVATING FACTOR | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2005-03-23 | — | — | EP | claimed |
| US-20040175776-A1 | Assay method for platelet-activating factor | ASUBIO PHARMA CO., LTD. (JP) | 2004-09-09 | — | — | US | claimed |
| EP-1390759-A2 | ASSAY METHOD FOR PLATELET-ACTIVATING FACTOR | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-02-25 | — | — | EP | claimed |
| WO-2002097435-A2 | ASSAY METHOD FOR PLATELET-ACTIVATING FACTOR | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2002-12-05 | — | — | WO | claimed |
| WO-2001068870-A2 | S-ADENOSYL-L-METHIONINE:PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE COMPOSITIONS AND METHODS FOR MODULATING LIPID BIOSYNTHESIS IN PLANTS | UNIVERSITY OF FLORIDA (US) | 2001-09-20 | — | — | WO | claimed |
| EP-4104186-A1 | METHOD FOR AN AUTOMATIC, SEMANTIC-BASED, FUNCTIONAL TISSUE ANNOTATION OF HISTOLOGICAL AND CELLULAR FEATURES IN ORDER TO IDENTIFY MOLECULAR FEATURES IN TISSUE SAMPLES | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |
| US-20220142948-A1 | COMPOSITIONS AND METHODS FOR MODULATING METABOLIC REGULATORS OF T CELL PATHOGENICITY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2022-05-12 | — | — | US | disclosed |
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-8198060-B2 | for drug screening; targets for anti-nematode vaccines, pesticides, and drugs | DIVERGENCE, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-7867749-B2 | Nematode phosphoethanolamine N-methyltransferase-like sequences | DIVERGENCE, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090318563-A1 | Nematicidal Compositions and Methods | DIVERGENCE, INC. | 2009-12-24 | — | — | US | disclosed |
| US-20040254150-A1 | Nematicidal compositions and methods | DIVERGENCE, INC. | 2004-12-16 | — | — | US | disclosed |
| WO-2004103070-A2 | NEMATICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2004-12-02 | — | — | WO | disclosed |
| US-20040175776-A1 | Assay method for platelet-activating factor | ASUBIO PHARMA CO., LTD. (JP) | 2004-09-09 | — | — | US | disclosed |
| US-20040091467-A1 | Nematode phosphoethanolamine n-methyltransferase-like sequences | MONSANTO TECHNOLOGY LLC | 2004-05-13 | — | — | US | disclosed |
| EP-1390759-A2 | ASSAY METHOD FOR PLATELET-ACTIVATING FACTOR | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
| WO-2004001011-A2 | NEMATODE PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE-LIKE SEQUENCES | DIVERGENCE, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| WO-2002097435-A2 | ASSAY METHOD FOR PLATELET-ACTIVATING FACTOR | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254150-A1 | Nematicidal compositions and methods | NISCH, PNMT, ATL3 | FDPS 397/4885LMNA 811/4885LAP3 1359/4885 |
| US-20070009981-A1 | Nematode phosphoethanolamine N-methyltransferase-like sequences | PNMT, HNMT, GNMT | FDPS 1607/4885LMNA 3432/4885LAP3 245/4885 |
| US-20040091467-A1 | Nematode phosphoethanolamine n-methyltransferase-like sequences | PNMT, HNMT, GNMT | FDPS 1607/4885LMNA 3432/4885LAP3 245/4885 |
| US-20090318563-A1 | Nematicidal Compositions and Methods | NISCH, PNMT, HNMT | FDPS 429/4885LMNA 942/4885LAP3 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.