Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 9/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836055 | 0.79 | GAA (0.37) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL3425141 | 0.78 | ALDH1A1 (0.40) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL9866030 | 0.77 | ALDH1A1 (0.39) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL12109574 | 0.76 | KMT2A (0.43) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL11085415 | 0.76 | ALDH1A1 (0.38) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL6025501 | 0.75 | ALDH1A1 (0.37) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL9865425 | 0.75 | GAA (0.38) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL15329996 | 0.73 | GAA (0.40) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL9838964 | 0.73 | GAA (0.36) | GAAHTTPKMALDH1A1MAPT | |
| SCHEMBL15023981 | 0.73 | ALDH1A1 (0.35) | GAAHTTPKMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888371-A | HEAT RESISTANCE, LIGHT RESISTANCE | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1989-12-19 | — | — | US | disclosed |