SCHEMBL9865425

SCHEMBL9865425

C=CC(=O)N1C(C)(C)CC(CC(O)(C2CC(C)(C)N(C(=O)C=C)C(C)(C)C2)C(O)(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.38
ALDH1A1 P00352 8/20 0.37
MAPT P10636 4/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
TSHR P16473 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
BLM P54132 2/20 0.37
ATM Q13315 2/20 0.37
HIF1A Q16665 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
USP2 O75604 1/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4E B2RXH2 4/20 0.34
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33
ALOX15 P16050 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9866030 0.81 ALDH1A1 (0.39) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL6025501 0.77 ALDH1A1 (0.37) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3425141 0.76 ALDH1A1 (0.40) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL10487560 0.75 GAA (0.38) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL15329996 0.75 GAA (0.40) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL15023981 0.74 ALDH1A1 (0.35) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL11085415 0.73 ALDH1A1 (0.38) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL9838964 0.72 GAA (0.36) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL12109574 0.71 KMT2A (0.43) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL28556085 0.66 ALDH1A1 (0.43) GAAALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5043460-A Discoloration inhibition; color photography FUJI PHOTO FILM CO., LTD. (JP) 1991-08-27 US disclosed
EP-0164130-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-08 EP disclosed
US-4745050-A Silver halide color photographic material and discoloration inhibitor therefor FUJI PHOTO FILM CO., LTD. (JP) 1988-05-17 US disclosed
US-4735893-A PYRAZOLO-AZOLE MAGNETA COUPLER, IMAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1988-04-05 US disclosed
EP-0164130-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed