SCHEMBL9866030

SCHEMBL9866030

C=CC(=O)N1C(C)(C)CC(C(O)(CC(O)(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)C2CC(C)(C)N(C(=O)C=C)C(C)(C)C2)CC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 4/20 0.39
TSHR P16473 4/20 0.39
MEN1 O00255 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
BLM P54132 2/20 0.39
ATM Q13315 2/20 0.39
HIF1A Q16665 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
USP2 O75604 1/20 0.39
CYP2D6 P10635 1/20 0.39
GAA P10253 8/20 0.38
LMNA P02545 3/20 0.35
ALOX15 P16050 2/20 0.35
GABBR2 O75899 2/20 0.35
GABBR1 Q9UBS5 2/20 0.35
GMNN O75496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9865425 0.81 GAA (0.38) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL6025501 0.79 ALDH1A1 (0.37) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL3425141 0.78 ALDH1A1 (0.40) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL10487560 0.77 GAA (0.38) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL15329996 0.77 GAA (0.40) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL15023981 0.77 ALDH1A1 (0.35) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL11085415 0.76 ALDH1A1 (0.38) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL12109574 0.74 KMT2A (0.43) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL9838964 0.73 GAA (0.36) ALDH1A1KMT2AMAPTTSHRMEN1
SCHEMBL28556085 0.69 ALDH1A1 (0.43) ALDH1A1KMT2AMAPTTSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5043460-A Discoloration inhibition; color photography FUJI PHOTO FILM CO., LTD. (JP) 1991-08-27 US disclosed
EP-0164130-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-11-08 EP disclosed
US-4745050-A Silver halide color photographic material and discoloration inhibitor therefor FUJI PHOTO FILM CO., LTD. (JP) 1988-05-17 US disclosed
US-4735893-A PYRAZOLO-AZOLE MAGNETA COUPLER, IMAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1988-04-05 US disclosed
EP-0164130-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed