SCHEMBL1048951

SCHEMBL1048951

CC(=O)c1ccccc1CC(C)N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SLC6A2 P23975 3/20 0.44
TAAR1 Q96RJ0 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
MAOA P21397 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
HTR1D P28221 1/20 0.41
HTR1B P28222 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR1E P28566 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839201 0.85 FOLH1 (0.50) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL11141533 0.85 FOLH1 (0.50) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL264745 0.85 FOLH1 (0.50) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL17374631 0.85 IRAK4 (0.47) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL725761 0.85 GABRA1 (0.50) IRAK4ALOX15ALOX12KMT2AKDM4E
SCHEMBL28766027 0.82 CYP2D6 (0.43) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL4551989 0.82 NOS3 (0.60) CYP2C9HTR2ANOS3NOS1NOS2
SCHEMBL4792772 0.82 NOS3 (0.60) CYP2C9HTR2ANOS3NOS1NOS2
SCHEMBL9723651 0.81 TAAR1 (0.44) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1
SCHEMBL19285676 0.81 GAA (0.49) CYP2D6CYP2C9CYP2C19SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms Pharmapotheca A, Inc. 2025-07-03 US disclosed
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms Pharmapotheca A Inc. (US) 2025-01-28 US disclosed
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms CHEMAPOTHECA, LLC (US) 2023-10-12 US disclosed
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms Pharmapotheca A, Inc. (US) 2023-08-08 US disclosed
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms PHARMAPOTHECA, LLC (US) 2021-09-21 US disclosed
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms PHARMAPOTHECA, LLC (US) 2021-02-04 US disclosed
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2020-11-12 US disclosed
EP-3478363-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS Chemapotheca LLC (US) 2019-05-08 EP disclosed
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC 2018-08-30 US disclosed
EP-2318126-B1 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE UNIV TEXAS (US) 2018-08-22 EP disclosed
WO-2017147375-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE DETERRENT DOSAGE FORMS CHEMAPOTHECA, LLC (US) 2017-08-31 WO disclosed
US-8017050-B2 Water purification membranes with improved fouling resistance BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-09-13 US disclosed
CN-102149450-A Water purification membranes with improved fouling resistance UNIV TEXAS 2011-08-10 CN disclosed
EP-2318126-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-05-11 EP disclosed
WO-2011005258-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-01-13 WO disclosed
US-20100059433-A1 POLYMER DEPOSITION AND MODIFICATION OF MEMBRANES FOR FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-11 US disclosed
US-20100051538-A1 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-03-04 US disclosed
WO-2010006196-A2 WATER PURIFICATION MEMBRANES WITH IMPROVED FOULING RESISTANCE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-14 WO disclosed
EP-1442006-A2 PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES Boehringer Ingelheim Chemicals, Inc. (US) 2004-08-04 EP disclosed
WO-2003037843-A2 PREPARATION OF AMPHETAMINES FROM PHENYLPROPANOLAMINES BOEHRINGER INGELHEIM CHEMICALS, INC. (US) 2003-05-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123310-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 CYP2D6 15/4885CYP2C9 4/4885CYP2C19 9/4885
US-11717498-B2 Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms SLC6A3, SLC6A2, CES2 CYP2D6 15/4885CYP2C9 5/4885CYP2C19 11/4885
US-20200352883-A1 METHODS OF TREATMENT USING AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, SLC6A2, CES2 CYP2D6 14/4885CYP2C9 5/4885CYP2C19 11/4885
US-20230321010-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 CYP2D6 17/4885CYP2C9 4/4885CYP2C19 8/4885
US-20210030699-A1 Methods of Treatment Using Amphetamine Controlled Release, Prodrug, and Abuse Deterrent Dosage Forms SLC6A3, SLC6A2, CES2 CYP2D6 15/4885CYP2C9 5/4885CYP2C19 11/4885
US-12208068-B2 Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms SLC6A3, CES2, SLC6A2 CYP2D6 17/4885CYP2C9 4/4885CYP2C19 8/4885
US-20250213502-A1 Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms SLC6A3, CES2, SLC6A2 CYP2D6 15/4885CYP2C9 4/4885CYP2C19 9/4885
US-20180243241-A1 AMPHETAMINE CONTROLLED RELEASE, PRODRUG, AND ABUSE-DETERRENT DOSAGE FORMS SLC6A3, CES2, SLC6A2 CYP2D6 15/4885CYP2C9 4/4885CYP2C19 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.