Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369461 | 0.95 | ADRB2 (0.60) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| SCHEMBL5015380 | 0.90 | ADRB2 (0.55) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL9420534 | 0.88 | ADRB2 (0.53) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| Ethylene Glycol SCHEMBL524375 | 0.84 | ALDH1A1 (0.62) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| Isobutamben SCHEMBL25178 | 0.84 | ADRB2 (0.65) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| Isobutamben SCHEMBL4756252 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| SCHEMBL24055108 | 0.81 | MAPT (0.49) | ADRB2ADRB1ADRB3LMNATSHR | |
| SCHEMBL16217637 | 0.81 | ALDH1A1 (0.61) | ADRB2ADRB1ADRB3LMNACYP1A2 | |
| SCHEMBL1784739 | 0.81 | ADRB2 (0.59) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL12559135 | 0.81 | ALDH1A1 (0.61) | ADRB2ADRB1ADRB3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0740528-B1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX THERAPEUTICS INC (US) | 2003-03-26 | — | — | EP | claimed |
| EP-0740528-A4 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP (US) | 1998-04-01 | — | — | EP | claimed |
| US-5733572-A | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-31 | — | — | US | claimed |
| EP-0740528-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1996-11-06 | — | — | EP | claimed |
| WO-1995015118-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1995-06-08 | — | — | WO | claimed |
| CN-111699217-B | Polyurethane resin composition | 三悠瑞克株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-111699217-A | Polyurethane resin composition | 三悠瑞克株式会社 | 2020-09-22 | — | — | CN | disclosed |
| US-20110004150-A1 | Transdermal Delivery Using Encapsulated Agent Activated by Ultrasound and or Heat | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2011-01-06 | — | — | US | disclosed |
| US-7232431-B1 | Intradermal incorporation of microparticles containing encapsulated drugs using low frequency ultrasound | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2007-06-19 | — | — | US | disclosed |
| US-20060034904-A1 | Transdermal delivery using emcapsulated agent activated by ultrasound and or heat | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2006-02-16 | — | — | US | disclosed |
| WO-2004060447-A2 | TRANSDERMAL DELIVERY USING ENCAPSULATED AGENT ACTIVATED BY ULTRASOUND AND/OR HEAT | ULTRA-SONIC TECHNOLOGIES, L.L.C. (US) | 2004-07-22 | — | — | WO | disclosed |
| US-6712805-B2 | Method and apparatus for intradermal incorporation of microparticles containing encapsulated drugs using low frequency ultrasound | ULTRA-SONIC TECHNOLOGIES, L.L.C. | 2004-03-30 | — | — | US | disclosed |
| US-20020138037-A1 | Method and apparatus for intradermal incorporation of microparticles containing encapsulated drugs using low frequency ultrasound | ULTRA-SONIC TECHNOLOGIES, L.L.C. | 2002-09-26 | — | — | US | disclosed |
| US-6414139-B1 | MIXTURE WITH GAS OR GAS PRECURSOR; DIAGNOSTIC IMAGING; ULTRASOUND AND COMPUTER AXIAL TOMOGRAPHY | IMARX THERAPEUTICS, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0740528-A4 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP (US) | 1998-04-01 | — | — | EP | disclosed |
| US-5733572-A | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-31 | — | — | US | disclosed |
| WO-1998009600-A2 | NOVEL SILICON AMPHIPHILIC COMPOUNDS AND THE USE THEREOF | IMARX PHARMACEUTICAL CORP. (US) | 1998-03-12 | — | — | WO | disclosed |
| CN-1137748-A | Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor | IMARX PHARMACEUTICAL CORP (US) | 1996-12-11 | — | — | CN | disclosed |
| EP-0740528-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995015118-A1 | GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION | IMARX PHARMACEUTICAL CORP. (US) | 1995-06-08 | — | — | WO | disclosed |