Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918471 | 0.86 | ADRB2 (0.56) | HTR6ADRB2HTR1DHTR2ACA1 | |
| Hydrochloric Acid SCHEMBL7558473 | 0.85 | ADRB2 (0.54) | HTR6ADRB2HTR1DHTR2ACA1 | |
| SCHEMBL10494798 | 0.81 | HTR6 (0.41) | HTR6ADRB2HTR1DHTR2ACA1 | |
| SCHEMBL10716608 | 0.80 | POLB (0.46) | HTR6ADRB2HTR1DHTR2A | |
| SCHEMBL25398994 | 0.80 | HTR6 (0.49) | HTR6ADRB2HTR1DHTR2A | |
| SCHEMBL10494711 | 0.79 | ADRB2 (0.47) | HTR6ADRB2HTR1DHTR2ACA1 | |
| SCHEMBL9597127 | 0.77 | HTR6 (0.35) | HTR6ADRB2HTR1D | |
| SCHEMBL10494731 | 0.77 | PLA2G4A (0.53) | — | |
| SCHEMBL10695378 | 0.76 | HTR6 (0.58) | HTR6HTR1D | |
| SCHEMBL25100768 | 0.76 | HTR6 (0.47) | HTR6ADRB2HTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816470-A | Heterocyclic compounds | GLAXO GROUP LIMITED | 1989-03-28 | — | — | US | disclosed |