Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ICMT | O60725 | 9/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716492 | 0.86 | ADRB2 (0.56) | POLBMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL10494794 | 0.80 | HTR6 (0.42) | HTR6ADRB2HTR1DHTR2A | |
| SCHEMBL25398994 | 0.80 | HTR6 (0.49) | HTR6ADRB2HTR1DHTR2AHASPIN | |
| SCHEMBL25100768 | 0.79 | HTR6 (0.47) | MAPTMAPK1HTR6ADRB2HTR1D | |
| SCHEMBL10717752 | 0.77 | PLA2G4A (0.59) | — | |
| SCHEMBL10718886 | 0.77 | ICMT (0.45) | POLBKDM4ELMNAMAPK1ICMT | |
| SCHEMBL10716617 | 0.74 | MEN1 (0.42) | POLBMAPTKDM4ELMNAMAPK1 | |
| SCHEMBL7749047 | 0.72 | HTR2A (0.68) | MAPTHTR6HTR2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10563984 | 0.72 | HTR1A (0.45) | MAPTKDM4ELMNAHTR6ADRB2 | |
| SCHEMBL4987596 | 0.72 | ICMT (0.54) | POLBMAPTKDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650810-A | OR INDOLE-5-THIOACETAMIDES | GLAXO GROUP LIMITED (GB) | 1987-03-17 | — | — | US | disclosed |