Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.37 |
| ▸ | IGF1R | P08069 | 6/20 | 0.37 |
| ▸ | FLT4 | P35916 | 6/20 | 0.37 |
| ▸ | KDR | P35968 | 6/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597127 | 0.85 | HTR6 (0.35) | HTR6HTR1DADRB2EGFRIGF1R | |
| SCHEMBL5918471 | 0.84 | ADRB2 (0.56) | HTR6HTR1DADRB2CA9CA1 | |
| SCHEMBL10466866 | 0.84 | PLA2G4A (0.44) | HTR6EGFRIGF1RFLT4KDR | |
| SCHEMBL10494723 | 0.84 | PLA2G4A (0.55) | HTR6EGFRIGF1RFLT4KDR | |
| Hydrochloric Acid SCHEMBL7558473 | 0.83 | ADRB2 (0.54) | HTR6HTR1DADRB2EGFRIGF1R | |
| SCHEMBL10494701 | 0.83 | EGFR (0.48) | HTR6EGFRIGF1RFLT4KDR | |
| SCHEMBL10465300 | 0.83 | EGFR (0.57) | HTR6ADRB2EGFRIGF1RFLT4 | |
| SCHEMBL10465297 | 0.82 | EGFR (0.53) | HTR6ADRB2EGFRIGF1RFLT4 | |
| SCHEMBL10494794 | 0.81 | HTR6 (0.42) | HTR6HTR1DADRB2CA9CA1 | |
| SCHEMBL10464116 | 0.80 | EGFR (0.58) | HTR6ADRB2EGFRIGF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816470-A | Heterocyclic compounds | GLAXO GROUP LIMITED | 1989-03-28 | — | — | US | disclosed |