SCHEMBL1049593

SCHEMBL1049593

CCc1cccc([SiH3])c1CC

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
TAAR1 Q96RJ0 2/20 0.43
HTR1A P08908 1/20 0.43
KCNH2 Q12809 2/20 0.36
SCN5A Q14524 2/20 0.36
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MGLL Q99685 1/20 0.33
PDK2 Q15119 1/20 0.33
NLRP3 Q96P20 1/20 0.33
DHFR P00374 1/20 0.32
DAO P14920 1/20 0.32
CACNA1C Q13936 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28734581 0.85 GABRA1 (0.37) GABRA1GABRB2TAAR1HTR1ADAO
SCHEMBL245773 0.82 GABRA1 (0.57) GABRA1GABRB2TAAR1HTR1AKCNH2
Methylamine SCHEMBL27545014 0.79 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
Methane SCHEMBL28776675 0.79 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL31498538 0.79 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL88662 0.79
Ammonia Solution, Strong SCHEMBL27320869 0.79 GABRA1 (0.55) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL307046 0.78 GABRA1 (0.48) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL3316034 0.78 GABRA1 (0.32) GABRA1GABRB2
SCHEMBL9000240 0.77 GABRA1 (0.52) GABRA1GABRB2TAAR1HTR1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113683716-A Ethylene polymerization catalyst, preparation method thereof and preparation method of ethylene-isobutylene copolymer 中国石油天然气股份有限公司 2021-11-23 CN claimed
US-20120178617-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US claimed
US-8163854-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-24 US claimed
US-20110015357-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
US-7847038-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-12-07 US claimed
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof MITSUBISHI PHARMA CORPORATION (JP) 2007-07-12 US claimed
EP-1719764-A1 METHOD OF ASYMMETRICALLY REDUCING 4- 5-(IMIDAZOL-1-YL)-2-MET HYLBENZOYL -3,5-DIMETHYL-BENZOIC ACID OR ESTER THEREOF Mitsubishi Pharma Corporation (JP) 2006-11-08 EP claimed
EP-4703367-A1 RUTHENIUM COMPLEX, METHOD FOR PRODUCING SILYL GROUP-CONTAINING COMPOUND, SILYL GROUP-CONTAINING POLYMER MIXTURE, CURABLE COMPOSITION, AND CURED PRODUCT Kaneka Corporation (JP) 2026-03-04 EP disclosed
EP-4703406-A1 HYDROLYZABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMER, CURABLE COMPOSITION, AND CURED PRODUCT Kaneka Corporation (JP) 2026-03-04 EP disclosed
US-20260049182-A1 RUTHENIUM COMPLEX, METHOD FOR PRODUCING SILYL GROUP-CONTAINING COMPOUND, SILYL GROUP-CONTAINING POLYMER MIXTURE, CURABLE COMPOSITION, AND CURED PRODUCT KANEKA CORPORATION (JP) 2026-02-19 US disclosed
US-20260049176-A1 HYDROLYZABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMER, CURABLE COMPOSITION, AND CURED PRODUCT KANEKA CORPORATION (JP) 2026-02-19 US disclosed
US-20250137196-A1 HYDROPHOBIC COATING AND METHOD OF APPLICATION TO SUBSTRATES GREEN THEME TECHNOLOGIES, INC. 2025-05-01 US disclosed
WO-2025090528-A1 HYDROPHOBIC COATING AND METHOD OF APPLICATION TO SUBSTRATES GREEN THEME TECHNOLOGIES, INC. (US) 2025-05-01 WO disclosed
US-20090018290-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-15 US disclosed
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof MITSUBISHI PHARMA CORPORATION (JP) 2007-07-12 US disclosed
EP-1719764-A1 METHOD OF ASYMMETRICALLY REDUCING 4- 5-(IMIDAZOL-1-YL)-2-MET HYLBENZOYL -3,5-DIMETHYL-BENZOIC ACID OR ESTER THEREOF Mitsubishi Pharma Corporation (JP) 2006-11-08 EP disclosed
EP-0191260-B1 PENTACOORDINATED SILICON COMPLEXES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PREPARING ORGANOSILANES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1989-05-31 EP disclosed
US-4617413-A Pentacoordinate silicon complexes, the process for their preparation and their application to the preparation of organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1986-10-14 US disclosed
EP-0191260-A1 Pentacoordinated silicon complexes, process for their preparation and their use in preparing organosilanes CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 1986-08-20 EP disclosed
US-4474976-A ARYLATION GENERAL ELECTRIC COMPANY (US) 1984-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049176-A1 HYDROLYZABLE SILYL GROUP-CONTAINING POLYOXYALKYLENE POLYMER, CURABLE COMPOSITION, AND CURED PRODUCT PSMA1, LIPA, SGMS1 GABRA1 3348/4885GABRB2 4317/4885TAAR1 2034/4885
US-20260049182-A1 RUTHENIUM COMPLEX, METHOD FOR PRODUCING SILYL GROUP-CONTAINING COMPOUND, SILYL GROUP-CONTAINING POLYMER MIXTURE, CURABLE COMPOSITION, AND CURED PRODUCT ILK, CROCC, SEM1 GABRA1 3297/4885GABRB2 3399/4885TAAR1 2876/4885
US-20090018290-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts TLL2, ESPL1, CCNL2 GABRA1 3885/4885GABRB2 4000/4885TAAR1 2393/4885
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof DDC, AADAC, ALG3 GABRA1 709/4885GABRB2 853/4885TAAR1 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.