Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 10/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497704 | 0.89 | ATG4B (0.44) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10497777 | 0.88 | THRA (0.46) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10498322 | 0.86 | HDAC4 (0.47) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10497836 | 0.85 | P4HB (0.47) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10498288 | 0.85 | SLC6A19 (0.45) | MAOAMAOBATG4BPLA2G1BTHRA | |
| SCHEMBL10498154 | 0.85 | THRA (0.44) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10497705 | 0.84 | THRA (0.44) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10497663 | 0.84 | THRA (0.43) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL10498942 | 0.84 | KCNK2 (0.43) | ATG4BPLA2G1BTHRATHRBCYP1A2 | |
| SCHEMBL9339736 | 0.84 | HDAC4 (0.44) | ATG4BPLA2G1BTHRATHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |