Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MPI | P34949 | 2/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | PMM2 | O15305 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502469 | 0.86 | METAP2 (0.59) | ALDH1A1MEN1KMT2AMPIG6PD | |
| SCHEMBL10503512 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMPIG6PD | |
| SCHEMBL10501312 | 0.82 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10748921 | 0.81 | MAPT (0.37) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10502370 | 0.81 | KMT2A (0.42) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10502151 | 0.75 | METAP2 (0.44) | ALDH1A1MEN1KMT2AMPIG6PD | |
| SCHEMBL10501717 | 0.75 | LMNA (0.35) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10501265 | 0.74 | MPI (0.49) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10502143 | 0.74 | METAP2 (0.45) | ALDH1A1MEN1KMT2AMPIAPOBEC3G | |
| SCHEMBL10501589 | 0.73 | METAP2 (0.61) | ALDH1A1MEN1KMT2AMPIG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |