Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502370 | 0.86 | KMT2A (0.42) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10748866 | 0.85 | L3MBTL1 (0.43) | MAPTGAANPSR1MEN1KMT2A | |
| SCHEMBL10502345 | 0.81 | ALDH1A1 (0.50) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10501717 | 0.80 | LMNA (0.35) | MAPTGAANPSR1MEN1KMT2A | |
| SCHEMBL10747422 | 0.77 | MEN1 (0.41) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL5916533 | 0.77 | KMT2A (0.45) | MAPTGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10747582 | 0.74 | METAP2 (0.40) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10746433 | 0.73 | KMT2A (0.38) | MAPTMEN1KMT2AALDH1A1MPI | |
| SCHEMBL10746666 | 0.71 | MAPT (0.45) | MAPTMEN1KMT2AALDH1A1MPI | |
| SCHEMBL10501715 | 0.70 | MEN1 (0.46) | MAPTNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0154851-A1 | Benzisoselenazolethiones,process for their preparation and pharmaceutical products containing these compounds | A. Nattermann & Cie. GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |