SCHEMBL1050352

SCHEMBL1050352

OCc1nc2cc(Cl)ccc2[nH]1

nearest known ligand 0.75

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.75
RHEB Q15382 4/20 0.52
NPSR1 Q6W5P4 1/20 0.46
F10 P00742 1/20 0.44
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
POLB P06746 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
EGFR P00533 1/20 0.42
CYP1A2 P05177 1/20 0.41
HRH4 Q9H3N8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9598311 0.86 TDP1 (0.57) TDP1RHEBF10RAB9ANPC1
SCHEMBL12636194 0.86 TDP1 (1.00) TDP1RHEBNPSR1F10RAB9A
SCHEMBL485294 0.84 TDP1 (0.53) TDP1F10RAB9ANPC1GAA
SCHEMBL18291859 0.82 TDP1 (0.51) TDP1F10RAB9ANPC1GAA
SCHEMBL5100448 0.82 TDP1 (0.51) TDP1F10RAB9ANPC1GAA
SCHEMBL7764723 0.82 GAA (0.64) TDP1F10RAB9ANPC1GAA
SCHEMBL4151145 0.82 TDP1 (0.51) TDP1F10RAB9ANPC1GAA
Hydrochloric Acid SCHEMBL4148629 0.81 TDP1 (0.50) TDP1F10RAB9ANPC1GAA
Hydrochloric Acid SCHEMBL30012925 0.81 TDP1 (0.50) TDP1F10RAB9ANPC1GAA
Hydrochloric Acid SCHEMBL5204712 0.81 TDP1 (0.50) TDP1F10RAB9ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138071-A1 SULFIDE GAS REMOVAL PROCESS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-05-21 US disclosed
US-20260014517-A1 HYDROGEN SULFIDE REMOVAL METHOD FROM DRILLING MUD COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-15 US disclosed
US-20260014514-A1 METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-15 US disclosed
US-20260014197-A1 DRUG DELIVERY SYSTEM IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2026-01-15 US disclosed
US-20260008009-A1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM A HYDROCARBON GASEOUS COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-08 US disclosed
US-20260002088-A1 PROCESS TO REMOVE HYDROGEN SULFIDE FROM A HYDROCARBON-CONTAINING GAS COMPOSITION KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2026-01-01 US disclosed
US-20250381514-A1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM SOUR GAS KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-12-18 US disclosed
US-12459862-B2 Cement paste composition KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-11-04 US disclosed
US-12427499-B2 Process for removing hydrogen sulfide from sour gases KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-30 US disclosed
US-12415726-B2 Process for simultaneous removal of hydrogen sulfide and heavy metals KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-16 US disclosed
EP-2094701-A2 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. (US) 2009-09-02 EP disclosed
US-7504426-B2 Heterocyclic compounds JANSSEN PHARMACEUTICA N.V. (BE) 2009-03-17 US disclosed
US-20080221148-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON INC 2008-09-11 US disclosed
WO-2008080001-A2 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. (US) 2008-07-03 WO disclosed
WO-2008080015-A2 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR PLEXXIKON, INC. (US) 2008-07-03 WO disclosed
EP-1671972-A1 Octahydropyrrolo[3,4-c]pyrrole derivatives Pfizer Limited (GB) 2006-06-21 EP disclosed
US-20060111416-A1 Octahydropyrrolo[3,4-C]pyrrole derivatives PFIZER INC. 2006-05-25 US disclosed
EP-1545532-A2 HETEROCYCLIC COMPOUNDS JANSSEN PHARMACEUTICA N.V. (BE) 2005-06-29 EP disclosed
US-20040058934-A1 Heterocyclic compounds JANSSEN PHARMACEUTIC, N.V. (BE) 2004-03-25 US disclosed
WO-2004022060-A2 (1H-BENZOIMIDAZOL-2-YL)-(PIPERAZINYL)-METHANONE DERIVATIVES AND RELATED COMPOUNDS AS HISTAMINE H4-RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS JANSSEN PHARMACEUTICA, N.V. (BE) 2004-03-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008009-A1 PROCESS FOR REMOVING HYDROGEN SULFIDE FROM A HYDROCARBON GASEOUS COMPOSITION HMOX2, HMOX1, SCO2 TDP1 4784/4885RHEB 3453/4885NPSR1 1528/4885
US-20260014517-A1 HYDROGEN SULFIDE REMOVAL METHOD FROM DRILLING MUD COMPOSITION TST, SOD1, SAMM50 TDP1 3048/4885RHEB 3508/4885NPSR1 2018/4885
US-20060111416-A1 Octahydropyrrolo[3,4-C]pyrrole derivatives DPYD, PAH, DHPS TDP1 1015/4885RHEB 1525/4885NPSR1 331/4885
US-20260002088-A1 PROCESS TO REMOVE HYDROGEN SULFIDE FROM A HYDROCARBON-CONTAINING GAS COMPOSITION SAMM50, SOD1, HNRNPH3 TDP1 4626/4885RHEB 3949/4885NPSR1 1511/4885
US-20040058934-A1 Heterocyclic compounds HRH4, HRH2, HRH1 TDP1 4329/4885RHEB 2027/4885NPSR1 157/4885
US-20260138071-A1 SULFIDE GAS REMOVAL PROCESS SAMM50, SRSF1, GTF2F1 TDP1 4119/4885RHEB 2718/4885NPSR1 2498/4885
US-20080221148-A1 COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR MAP3K20, MAP3K13, MAP3K8 TDP1 631/4885RHEB 567/4885NPSR1 4558/4885
US-20260014514-A1 METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR SOD1, MAFG, HMOX2 TDP1 4234/4885RHEB 4231/4885NPSR1 3431/4885
US-20260014197-A1 DRUG DELIVERY SYSTEM IPO8, SLC39A11, SLC2A8 TDP1 3457/4885RHEB 1237/4885NPSR1 3825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.