Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HPN | P05981 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | VCAM1 | P19320 | 12/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647467 | 0.81 | ALOX15 (0.68) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL645860 | 0.81 | ALOX15 (0.68) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL648287 | 0.79 | ALOX15 (0.63) | ALOX15HPNMAPTSIRT5VCAM1 | |
| Probucol SCHEMBL4150 | 0.78 | HPN (1.00) | ALOX15HPNMAPTSIRT5VCAM1 | |
| Probucol SCHEMBL5143451 | 0.78 | HPN (1.00) | ALOX15HPNMAPTSIRT5VCAM1 | |
| Probucol SCHEMBL8344652 | 0.77 | ALOX15 (0.95) | ALOX15HPNMAPTSIRT5VCAM1 | |
| Probucol SCHEMBL4620631 | 0.77 | ALOX15 (0.95) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL9506457 | 0.77 | HPN (0.79) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL646329 | 0.76 | HPN (0.59) | ALOX15HPNMAPTSIRT5VCAM1 | |
| SCHEMBL10504021 | 0.76 | HPN (0.59) | ALOX15HPNMAPTSIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155474-B1 | BIS-,TRIS-, TETRAKIS-AND PENTAKIS-(SUBSTITUTED HYDROXY-PHENYLTHIO)-ALKANES AND CYCLOALKANES AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |
| US-4612341-A | Tri- and tetra-(substituted hydroxyphenylthio) alkane and cycloalkane stabilizers | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| US-4560799-A | FOR RUBBERS, ABS RESIN, POLYESTERS AND POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0155474-A1 | Bis-,tris-, tetrakis-and pentakis-(substituted hydroxy-phenylthio)-alkanes and cycloalkanes and compositions containing them | CIBA-GEIGY AG (CH) | 1985-09-25 | — | — | EP | disclosed |