Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 12/20 | 0.42 |
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675079 | 0.89 | KDM1A (0.43) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL1051243 | 0.85 | KDM1A (0.44) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL1049210 | 0.83 | KDM1A (0.39) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL27655325 | 0.81 | AKR1B1 (0.47) | KDM1A | |
| SCHEMBL27675055 | 0.79 | HTR1B (0.38) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL1049417 | 0.78 | MMP1 (0.40) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL30007810 | 0.77 | HTR1B (0.65) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL667918 | 0.77 | HTR1B (0.65) | KDM1AHTR1BHTR1DSLC6A4HRH1 | |
| SCHEMBL30359494 | 0.76 | NCF1 (0.49) | KDM1AHTR1BHTR1D | |
| SCHEMBL9466089 | 0.76 | KDM1A (0.49) | KDM1AHTR1BHTR1DSLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868036-B2 | Organic compounds | NOVARTIS AG (CH) | 2011-01-11 | — | — | US | disclosed |
| US-20080058320-A1 | Organic Compounds | NOVARTIS AG (CH) | 2008-03-06 | — | — | US | disclosed |
| EP-1725530-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005090304-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058320-A1 | Organic Compounds | REN, AGTR1, ADH1C | KDM1A 1849/4885HTR1B 517/4885HTR1D 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.