SCHEMBL667918

SCHEMBL667918

COCCOc1cccc2ccccc12

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 11/20 0.65
HTR1D P28221 2/20 0.64
SLC6A4 P31645 2/20 0.62
HRH1 P35367 1/20 0.62
KCNA3 P22001 1/20 0.61
KDM1A O60341 1/20 0.59
NR2E1 Q9Y466 1/20 0.57
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
HPGD P15428 1/20 0.55
TDP1 Q9NUW8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007810 1.00 HTR1B (0.65) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL667325 0.95 KDM4E (0.61) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL667906 0.95 KDM4E (0.61) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL10984843 0.91 KCNA3 (0.69) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL5289923 0.90 HTR1B (0.77) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL18574221 0.88 HTR1B (0.47) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL11057929 0.86 KCNA3 (0.54) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL8642238 0.84 HTR1B (0.69) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL8674828 0.84 HTR1B (0.69) HTR1BHTR1DSLC6A4HRH1KCNA3
SCHEMBL9466089 0.84 KDM1A (0.49) HTR1BHTR1DSLC6A4HRH1KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111522198-B Resist composition and pattern forming method 信越化学工业株式会社 2024-01-26 CN disclosed
US-11840015-B2 Composition for optical three-dimensional shaping, three-dimensionally shaped article, and method for producing same OKAMOTO CHEMICAL INDUSTRY CO., LTD. (JP) 2023-12-12 US disclosed
EP-3904414-B1 COMPOSITION FOR OPTICAL THREE-DIMENSIONAL SHAPING, THREE-DIMENSIONALLY SHAPED ARTICLE, AND METHOD FOR PRODUCING SAME OKAMOTO CHEMICAL IND CO LTD (JP) 2023-12-06 EP disclosed
CN-116360211-A Chemically amplified positive photosensitive resin composition, protective film, and element having protective film 奇美实业股份有限公司 2023-06-30 CN disclosed
CN-110963952-B Onium salt, resist composition and pattern forming method 信越化学工业株式会社 2022-10-21 CN disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-11448962-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-09-20 US disclosed
EP-3904414-A1 COMPOSITION FOR OPTICAL THREE-DIMENSIONAL SHAPING, THREE-DIMENSIONALLY SHAPED ARTICLE, AND METHOD FOR PRODUCING SAME Okamoto Chemical Industry Co., Ltd. (JP) 2021-11-03 EP disclosed
US-20210229344-A1 COMPOSITION FOR OPTICAL THREE-DIMENSIONAL SHAPING, THREE-DIMENSIONALLY SHAPED ARTICLE, AND METHOD FOR PRODUCING SAME OKAMOTO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-07-29 US disclosed
CN-111522198-A Resist composition and pattern forming method 信越化学工业株式会社 2020-08-11 CN disclosed
US-7868036-B2 Organic compounds NOVARTIS AG (CH) 2011-01-11 US disclosed
US-20080058320-A1 Organic Compounds NOVARTIS AG (CH) 2008-03-06 US disclosed
US-20080058320-A1 Organic Compounds NOVARTIS AG (CH) 2008-03-06 US disclosed
US-20070066582-A1 Diaminoalcohols as therapeutic compounds SPEEDEL EXPERIMENTA AG (CH) 2007-03-22 US disclosed
US-20070066582-A1 Diaminoalcohols as therapeutic compounds SPEEDEL EXPERIMENTA AG (CH) 2007-03-22 US disclosed
EP-1764099-A2 Diaminoalcohol derivatives for the treatment of Alzheimer, malaria, HIV Speedel Experimenta AG (CH) 2007-03-21 EP disclosed
CN-1934082-A Organic compounds SPEEDEL EXPERIMENTA AG (CH) 2007-03-21 CN disclosed
WO-2005090304-A1 ORGANIC COMPOUNDS SPEEDEL EXPERIMENTA AG (CH) 2005-09-29 WO disclosed
CN-1117035-C Water treatment agent NIPPON CATALYTIC CHEM IND (JP) 2003-08-06 CN disclosed
CN-1151380-A Water treatment agent NIPPON CATALYTIC CHEM IND (JP) 1997-06-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066582-A1 Diaminoalcohols as therapeutic compounds CTSD, CTSL, CTSC HTR1B 1359/4885HTR1D 1391/4885SLC6A4 3493/4885
US-11448962-B2 Resist composition and patterning process PAG1, LIFR, GIGYF2 HTR1B 4427/4885HTR1D 4701/4885SLC6A4 1901/4885
US-20080058320-A1 Organic Compounds REN, AGTR1, ADH1C HTR1B 517/4885HTR1D 698/4885SLC6A4 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.