Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652591 | 0.92 | CCKBR (0.50) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10507702 | 0.79 | OPRK1 (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL17969884 | 0.78 | CCKBR (0.51) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10511185 | 0.77 | OPRD1 (0.40) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10738300 | 0.77 | GABRA1 (0.59) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10510429 | 0.76 | LMNA (0.59) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL16104663 | 0.72 | HTR1A (0.36) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL10736395 | 0.71 | OPRK1 (0.39) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10507732 | 0.70 | LMNA (0.42) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL10510402 | 0.69 | LMNA (0.40) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172526-B1 | BENZODIAZEPINES, PROCESS FOR THEIR PREPARATION AND THEIR USE | Troponwerke GmbH & Co. KG (DE) | 1989-10-04 | — | — | EP | disclosed |
| US-4647560-A | COGNITION ACTIVATORS | TROPONWERKE GMBH & CO. KG (DE) | 1987-03-03 | — | — | US | disclosed |