SCHEMBL10508258

SCHEMBL10508258

Cc1ccc(C(=O)C(O)c2ccc(C)cc2)cc1.Cc1ccccc1S(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
LMNA P02545 1/20 0.46
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPSR1 Q6W5P4 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
CYP2D6 P10635 1/20 0.36
MAPK1 P28482 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
HCRTR2 O43614 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10505589 0.89 CES2 (0.44) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL708292 0.89 LMNA (0.62) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL10708802 0.85 CYP2D6 (0.36) CES2CES1ALDH1A1NPSR1CYP1A2
SCHEMBL66875 0.80 CES2 (0.58) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL66803 0.78 LMNA (0.74) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL66647 0.78 LMNA (0.74) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL11213797 0.78 LMNA (0.55) CES2CES1LMNAALDH1A1KDM4E
Benzoin SCHEMBL60546 0.78 LMNA (0.64) CES2CES1LMNAALDH1A1KDM4E
Mandelic Acid SCHEMBL16499230 0.78 LMNA (0.58) CES2CES1LMNAALDH1A1KDM4E
SCHEMBL216825 0.77 ALDH1A1 (0.49) LMNAALDH1A1KDM4ETSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4837350-A Process for the preparation of benzoin sulfonates CIBA-GEIGY CORPORATION (US) 1989-06-06 US disclosed