SCHEMBL1050874

SCHEMBL1050874

C=CCc1ccc(O)c(O)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 5/20 0.50
GABRB2 P47870 5/20 0.50
POLB P06746 2/20 0.43
AKR1B1 P15121 2/20 0.42
XDH P47989 2/20 0.42
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
GAA P10253 3/20 0.41
CNR2 P34972 3/20 0.41
MAPT P10636 2/20 0.41
CNR1 P21554 2/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH2 P05091 1/20 0.41
HPGD P15428 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALOX5 P09917 3/20 0.40
GABRB1 P18505 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752469 0.86 GABRA1 (0.52) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL1007913 0.84 GABRA1 (0.46) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL11118423 0.82 GABRA1 (0.48) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL978929 0.81 GABRA1 (0.55) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL132917 0.78 ALOX5 (0.46) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL1869397 0.78 ALOX5 (0.46) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL7943871 0.78 GABRA1 (0.52) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL23919938 0.76 AMY1A (0.47) POLBMEN1KMT2AGAAMAPT
SCHEMBL8072029 0.76 GABRA1 (0.46) GABRA1GABRB2POLBAKR1B1XDH
SCHEMBL9268985 0.76 GABRA1 (0.50) GABRA1GABRB2POLBAKR1B1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105481655-A Method for core-shell catalyst to convert bagasse lignin into phenol compound UNIV NORTHEAST PETROLEUM 2016-04-13 CN claimed
EP-2318477-B1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MAT USA INC (US) 2019-06-05 EP disclosed
CN-105541559-A Method for producing aryl oxygenated compound from lignin in presence of perovskite oxide UNIV NORTHEAST PETROLEUM 2016-05-04 CN disclosed
CN-105481655-A Method for core-shell catalyst to convert bagasse lignin into phenol compound UNIV NORTHEAST PETROLEUM 2016-04-13 CN disclosed
CN-104203891-A Process for producing alkoxy-hydroxybenzaldehydes substantially free of alkyl-alkoxy-hydroxybenzaldehydes RHODIA OPERATIONS 2014-12-10 CN disclosed
US-8252704-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2012-08-28 US disclosed
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-10-27 US disclosed
US-7985350-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-07-26 US disclosed
EP-2318477-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FujiFilm Electronic Materials USA, Inc. (US) 2011-05-11 EP disclosed
US-20110091651-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-04-21 US disclosed
US-7871536-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2011-01-18 US disclosed
WO-2010005937-A1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2010-01-14 WO disclosed
US-20090291210-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2009-11-26 US disclosed
CN-1681807-A Antidepressant cycloalkylamine derivatives of 2, 3-dihydro-1, 4-benzodioxan WYETH CORP (US) 2005-10-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110259242-A1 Additives to Prevent Degradation of Cyclic Alkene Derivatives GPX4, GPX1, NFE2L2 GABRA1 3716/4885GABRB2 2890/4885POLB 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.