Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512932 | 0.83 | ALDH1A1 (0.48) | MGLLPOLBCYP2C19NPC1RAB9A | |
| SCHEMBL10513531 | 0.83 | MGLL (0.43) | MGLLPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL11153193 | 0.83 | L3MBTL1 (0.47) | MGLLPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL10514900 | 0.81 | MGLL (0.41) | MGLLL3MBTL1NPC1RAB9AALDH1A1 | |
| SCHEMBL11154111 | 0.80 | KMT2A (0.56) | MGLLMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11159483 | 0.80 | OPRM1 (0.44) | POLBALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL11158087 | 0.80 | KCNH2 (0.47) | MGLLPOLBL3MBTL1NPC1RAB9A | |
| SCHEMBL11150886 | 0.80 | CYP2D6 (0.47) | MGLLL3MBTL1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11154544 | 0.79 | SIGMAR1 (0.52) | MGLLMAPTALDH1A1SMN1; SMN2FAAH | |
| SCHEMBL11149286 | 0.78 | SIGMAR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325953-A | 4-Aryl-4-aryloxypiperidines | JOHN WYETH AND BROTHER LIMITED (GB) | 1982-04-20 | — | — | US | disclosed |