Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871169 | 0.87 | KDM4B (0.34) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL10869929 | 0.87 | ATP4A (0.35) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL10519036 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL10520147 | 0.76 | LSS (0.41) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL10517590 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPTHSD17B10NPC1GFER | |
| SCHEMBL10868918 | 0.73 | NOS1 (0.41) | MAPTMEN1KMT2AATP4AATP4B | |
| SCHEMBL10520078 | 0.72 | LSS (0.39) | ALDH1A1MAPTHSD17B10NPC1KDM4E | |
| SCHEMBL10521092 | 0.71 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL10518366 | 0.65 | MAPT (0.53) | ALDH1A1MAPTHSD17B10NPC1KDM4E | |
| SCHEMBL10520739 | 0.63 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10NPC1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183191-A1 | Thienylthiazole compounds | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1986-06-04 | — | — | EP | disclosed |