Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804409 | 0.88 | TK1 (0.32) | LMNAALBALDH1A1MAPK1TK1 | |
| SCHEMBL10522154 | 0.87 | ALDH1A1 (0.40) | LMNAALBALDH1A1MAPK1ABL1 | |
| SCHEMBL23258398 | 0.85 | LMNA (0.43) | LMNAALBALDH1A1MAPK1ABL1 | |
| SCHEMBL5638638 | 0.84 | LMNA (0.42) | LMNAALBALDH1A1MAPK1ABL1 | |
| SCHEMBL1421772 | 0.84 | LMNA (0.42) | LMNAALBALDH1A1MAPK1ABL1 | |
| SCHEMBL14154578 | 0.80 | LMNA (0.39) | LMNAALBALDH1A1MAPK1ABL1 | |
| SCHEMBL17804440 | 0.79 | POLB (0.38) | TK1 | |
| SCHEMBL5179808 | 0.78 | TK1 (0.49) | LMNACYP1A2TSHRTK1BLM | |
| SCHEMBL5179815 | 0.78 | TK1 (0.49) | LMNACYP1A2TSHRTK1BLM | |
| SCHEMBL3813740 | 0.78 | LMNA (0.41) | LMNAALBALDH1A1MAPK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016388-A1 | METHOD OF DETECTING AND MONITORING LEVELS OF 3'-AMINO-3'-DEOXYTHYMIDINE IN BODY FLUIDS AND ANTIBODIES FOR SAME | THE UAB RESEARCH FOUNDATION (US) | 1993-08-19 | — | — | WO | disclosed |