Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524213 | 0.91 | PTGS2 (0.57) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10526302 | 0.91 | PTGS2 (0.57) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10526127 | 0.87 | PTGS2 (0.60) | PTGS2CNR2AKR1C3 | |
| SCHEMBL10526172 | 0.86 | PTGS2 (0.62) | PTGS2CNR2AKR1C3 | |
| SCHEMBL10816176 | 0.85 | PTGS2 (0.60) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10525264 | 0.84 | PTGS2 (0.56) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10527799 | 0.84 | PTGS2 (0.64) | PTGS2CNR2AKR1C3 | |
| SCHEMBL10523837 | 0.83 | PTGS2 (0.59) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10817893 | 0.81 | LMNA (0.49) | PTGS2 | |
| SCHEMBL10526684 | 0.77 | PTGS2 (0.67) | PTGS2CNR2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188803-B1 | PIPERAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4696929-A | Derivative of piperazine having anti-allergic and anti-inflammatory action | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |