Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524213 | 0.90 | PTGS2 (0.57) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10526302 | 0.90 | PTGS2 (0.57) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10524488 | 0.81 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL10816176 | 0.79 | PTGS2 (0.60) | PKMHIF1APTGS2 | |
| SCHEMBL10815513 | 0.75 | TSHR (0.57) | LMNACYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL10525346 | 0.75 | PTGS2 (0.67) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10526684 | 0.75 | PTGS2 (0.67) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10817886 | 0.73 | P2RX3 (0.41) | MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10524337 | 0.73 | PTGS2 (0.69) | LMNACYP1A2CYP2C9PMP22MEN1 | |
| SCHEMBL10526360 | 0.72 | PTGS2 (0.61) | LMNACYP1A2CYP2C9PMP22MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696929-A | Derivative of piperazine having anti-allergic and anti-inflammatory action | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |