Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524213 | 0.89 | PTGS2 (0.57) | PTGS2CNR2PKMCNR1AKR1C3 | |
| SCHEMBL10526302 | 0.89 | PTGS2 (0.57) | PTGS2CNR2PKMCNR1AKR1C3 | |
| SCHEMBL10524488 | 0.85 | PTGS2 (0.54) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10817893 | 0.79 | LMNA (0.49) | PTGS2PKMHIF1A | |
| SCHEMBL10816172 | 0.75 | P2RX3 (0.37) | PTGS2CNR2HTR1ACNR1 | |
| SCHEMBL11159263 | 0.74 | PTGS2 (0.80) | PTGS2CNR2HTR1APKMPTGS1 | |
| SCHEMBL10526684 | 0.74 | PTGS2 (0.67) | PTGS2CNR2PTGS1GLO1HIF1A | |
| SCHEMBL10525346 | 0.74 | PTGS2 (0.67) | PTGS2CNR2PTGS1GLO1HIF1A | |
| SCHEMBL8031505 | 0.73 | PTGS2 (0.79) | PTGS2CNR2HTR1APKMPTGS1 | |
| SCHEMBL10880869 | 0.73 | PTGS2 (0.62) | PTGS2CNR2PTGS1GLO1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696929-A | Derivative of piperazine having anti-allergic and anti-inflammatory action | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |