Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.57 |
| ▸ | CNR2 | P34972 | 3/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524213 | 1.00 | PTGS2 (0.57) | PTGS2CNR2CNR1AKR1C3MEN1 | |
| SCHEMBL10524488 | 0.91 | PTGS2 (0.54) | PTGS2CNR2CNR1AKR1C3 | |
| SCHEMBL10817893 | 0.90 | LMNA (0.49) | PTGS2MEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10816176 | 0.89 | PTGS2 (0.60) | PTGS2CNR2CNR1AKR1C3PKM | |
| SCHEMBL10526684 | 0.86 | PTGS2 (0.67) | PTGS2CNR2AKR1C3MEN1CYP1A2 | |
| SCHEMBL10525346 | 0.86 | PTGS2 (0.67) | PTGS2CNR2AKR1C3MEN1CYP1A2 | |
| SCHEMBL10524337 | 0.85 | PTGS2 (0.69) | PTGS2CNR2AKR1C3MEN1CYP1A2 | |
| SCHEMBL10526360 | 0.83 | PTGS2 (0.61) | PTGS2CNR2CNR1AKR1C3MEN1 | |
| SCHEMBL10526127 | 0.76 | PTGS2 (0.60) | PTGS2CNR2AKR1C3MEN1CYP1A2 | |
| SCHEMBL11021973 | 0.75 | PTGS2 (0.67) | PTGS2CNR2AKR1C3MEN1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188803-B1 | PIPERAZINE DERIVATIVE | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4696929-A | Derivative of piperazine having anti-allergic and anti-inflammatory action | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1987-09-29 | — | — | US | disclosed |
| EP-0188803-A1 | Piperazine derivative | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1986-07-30 | — | — | EP | disclosed |