Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533120 | 0.79 | PTGS2 (0.52) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL7576854 | 0.74 | PTGS2 (0.51) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| Acetic Acid SCHEMBL28881805 | 0.74 | METTL3 (0.45) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL8370092 | 0.69 | CXCL8 (0.42) | PTGS2MEN1KMT2AAKR1B10ABCB11 | |
| SCHEMBL8611754 | 0.69 | ALDH1A1 (0.62) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL9735497 | 0.68 | PTGS2 (0.48) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL28543940 | 0.65 | MEN1 (0.50) | MEN1KMT2AMAPK1TSHRTP53 | |
| SCHEMBL7581152 | 0.65 | ALDH1A1 (0.46) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL24021602 | 0.64 | MEN1 (0.56) | PTGS2MEN1KMT2AMAPK1METTL3 | |
| SCHEMBL2906104 | 0.64 | TSHR (0.49) | PTGS2KMT2AMAPK1AKR1B10ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4879311-A | ANALGESIC, ANTIINFLAMMATORY | INVERNI DELLA BEFFA S.P.A. (IT) | 1989-11-07 | — | — | US | disclosed |
| EP-0301834-A2 | Derivatives of benzoyloxyacetic acid, and preparation and formulations thereof for therapeutic use | IDB HOLDING S.p.A. (IT) | 1989-02-01 | — | — | EP | disclosed |