Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CLCN2 | P51788 | 3/20 | 0.51 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407555 | 0.81 | ALDH1A1 (0.55) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL11274238 | 0.78 | ALDH1A1 (0.55) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL9768040 | 0.75 | ALDH1A1 (0.52) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL5320792 | 0.71 | RAB9A (0.65) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL28095642 | 0.71 | AGTR1 (0.65) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL19707725 | 0.71 | MAPT (0.76) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL11183196 | 0.71 | AGTR1 (0.51) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL9735497 | 0.70 | PTGS2 (0.48) | ALDH1A1MAPTGAAPTGS2MEN1 | |
| SCHEMBL7581152 | 0.69 | ALDH1A1 (0.46) | ALDH1A1AGTR1MAPTGAASMN1; SMN2 | |
| SCHEMBL24021602 | 0.69 | MEN1 (0.56) | ALDH1A1MAPTGAASMN1; SMN2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840758-A | USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES | ABBOTT LABORATORIES (US) | 1998-11-24 | — | — | US | disclosed |