Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375490 | 0.95 | HRH3 (0.43) | OPRM1OPRK1HRH3 | |
| SCHEMBL9687389 | 0.93 | OPRM1 (0.42) | OPRM1OPRK1CHRNA7 | |
| SCHEMBL10763691 | 0.89 | OPRM1 (0.43) | OPRM1OPRK1HRH3CHRNA7 | |
| SCHEMBL10538576 | 0.80 | ALDH1A1 (0.43) | OPRM1OPRK1HRH3CHRNA7 | |
| SCHEMBL10538934 | 0.76 | PPID (0.39) | OPRM1OPRK1HRH3 | |
| SCHEMBL10376883 | 0.75 | HRH3 (0.43) | OPRM1OPRK1HRH3 | |
| SCHEMBL10375596 | 0.75 | HRH3 (0.43) | OPRM1OPRK1HRH3 | |
| SCHEMBL10761904 | 0.75 | HRH3 (0.43) | OPRM1OPRK1HRH3 | |
| SCHEMBL10375779 | 0.75 | HRH3 (0.43) | OPRM1OPRK1HRH3CHRNA7 | |
| SCHEMBL10921603 | 0.75 | ABCB1 (0.45) | OPRM1OPRK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4800207-A | Hexahydropyrrolizine compounds useful as analgesics | MCNEILAB, INC. (US) | 1989-01-24 | — | — | US | disclosed |